Don’t Lower High Blood Pressure Too Early with Medications
New problems can arise – doctors warn of risks from treatment that’s too rapid

Key findings of the article:
- Doctors warn of risks when high blood pressure is lowered too quickly with medications
- The threshold values for normal and treatment-requiring blood pressure change occasionally
- Currently, blood pressure of 120/80 to 129/84 mmHg is considered “normal”; hypertension begins at 140/90 mmHg
Those who don’t belong to the fortunate people with clearly normal blood pressure, but rather lie slightly above it, have been confronted with different and often confusing messages for years. At its core, it’s always about when blood pressure is considered in need of treatment and what value should be targeted as the goal of drug therapy.
While decades ago an upper value of 100 plus age was acceptable (for a 60-year-old, that would correspond to 160 mmHg), doctors today draw much lower limits. The so-called SPRINT study even concluded in 2015 that it would be best to push the upper value below 120 mmHg.
A recommendation against whose uncritical adherence many experts, such as those from the German Heart Foundation, warn, because such a drastic reduction in blood pressure is not suitable for all patients and can have negative effects, especially in older people.
Current Blood Pressure Classification
The current threshold values according to the classification of the World Health Organization WHO, the European Society of Cardiology, and the German Hypertension League:
Blood Pressure Classification:
- Optimal: below 120/80 mmHg
- Normal: 120-129/80-84 mmHg
- High-normal: 130-139/85-89 mmHg (no medications needed yet)
- Grade 1 Hypertension (mild): 140-159/90-99 mmHg
- Grade 2 Hypertension (moderate): 160-179/100-109 mmHg
- Grade 3 Hypertension (severe): ≥ 180/110 mmHg
Drug treatment is therefore only required from values of 140/90 mmHg onwards, when Grade 1 hypertension, mild high blood pressure, is present.
The Controversial Borderline Range
Experts particularly disagree on how to deal with values in the range of 130-140/85-90 mmHg. Is this still healthy or already sick? Doctors from the USA have decided on the latter.
The American College of Cardiology has introduced an additional category in its guidelines: “Stage 1 Hypertension.” This is particularly significant because American cardiologists already consider this value to require treatment: patients in whom it is repeatedly measured are therefore prescribed blood pressure-lowering medications.
American vs. European Guidelines
Often the USA are pioneers in medicine, and Europeans follow a little later. In the case of assessing slightly elevated blood pressure values, however, this is not emerging. At their congress in September 2018, the European Society of Cardiology decided to maintain the previous threshold values.
Accordingly, drug treatment only becomes necessary from a blood pressure of 140/90 mmHg – not at the lower American threshold values.
Munich Study: Negative Effects of Early Treatment
A team of scientists from the Technical University of Munich (TUM) and the Helmholtz Center Munich now supports the European decision. The researchers concluded that such a low threshold for treatment provides no protection against fatal cardiovascular disease.
Rather, taking tablets for high blood pressure can have negative consequences for the patients’ psyche – and thereby even negatively affect heart health; thus achieving the opposite of what the therapy is actually supposed to accomplish.
“The idea behind the US guidelines is to lower blood pressure as early as possible and motivate patients through the diagnosis of a disease,” explains Karl-Heinz Ladwig, researcher at the Clinic for Psychosomatic Medicine and Psychotherapy at the TUM University Hospital rechts der Isar.
Together with his team, he analyzed data from nearly 12,000 patients over a period of ten years. The result: In the category “Stage 1 Hypertension” newly created by American cardiologists, the risk of dying from cardiovascular disease was not significantly higher than with normal blood pressure.
The Psychological “Labeling Effect”
Karl-Heinz Ladwig also sees the motivational effect postulated by US doctors as questionable. As justification, he cites the example of patients with dangerously high blood pressure: In this group, smoking and lack of exercise are particularly widespread – both are among the biggest risk factors for high blood pressure.
“This shows that many do not change their lifestyle despite the diagnosis”
Karl-Heinz Ladwig, TUM researcher
In people with borderline blood pressure between 130-139/85-89 mmHg, a completely different risk factor can come into play. It has been known for some time that there are manifold interactions between psychological crises, depression, and cardiovascular events.
The Munich scientists had shown in an earlier study that depression burdens the cardiovascular system similarly to high cholesterol levels and obesity.
As the Munich study revealed, depressive moods were found in about half of the men and women who took medications for their high blood pressure. This was only the case in about one-third of patients who did not seek treatment.
“We assume that this is a labeling effect. When you are officially labeled as ‘sick,’ it affects your psychological health.”
Karl-Heinz Ladwig
According to calculations by the American College of Cardiology, the new guidelines in the USA will increase the proportion of adults with a diagnosis of high blood pressure from 32 to 46 percent. “14 percent will thus be subjected to additional psychological pressure,” says Ladwig – “without there being a significantly higher danger for them to develop fatal cardiovascular disease and without a motivational effect of the diagnosis being expected.”
Lowering Blood Pressure Naturally
The European Society of Cardiology recommends lowering blood pressure values naturally when blood pressure is in the high-normal range. Even though it’s difficult and many don’t maintain it long-term: Through lifestyle changes, even people with pronounced high blood pressure can manage to do without medications or at least significantly reduce their dosage.
Natural blood pressure reduction – the most effective measures:
- Weight loss: on average 2 mmHg per kilogram lost
- Regular physical activity: reduction of 5-10 mmHg possible
- Salt reduction: less sodium in the diet
- Reduce alcohol: moderate consumption or abstinence
- Smoking cessation: immediate positive effects
- Stress reduction: chronic stress burdens the cardiovascular system
According to the German Heart Foundation, blood pressure can be lowered particularly effectively through weight loss. Three-quarters of all overweight people suffer from high blood pressure. Experts point out that not all sports are equally suitable and that any increase in daily movement helps.
Conclusion and Recommendations
The Munich scientists see it as “fundamentally wrong” if Europeans were to adopt the guidelines from the USA. Early drug treatment of borderline blood pressure values offers no demonstrable protection but can cause psychological stress.
Instead of hastily turning to medications, lifestyle measures should take priority for values in the high-normal range. Diet can affect not only blood pressure but also influence other health risks.
An individualized consideration of each patient remains crucial – not every borderline value requires immediate drug intervention.
This article is based on the original contribution by Pamela Dörhöfer in the Frankfurter Rundschau and presents current scientific findings on blood pressure treatment. It serves for information purposes and does not replace individual medical consultation.
Original source: Frankfurter Rundschau – “Don’t lower high blood pressure too early with medications”